The other design factor aside from the text is the imagery that you can use. Many of the newsletter templates will come equipped with basic clip art or graphics. Others will include areas where you can paste in your own graphs, photographs, or other graphic items that help round out the information. It's important to remember that the first thing that people often look at, even before the headlines, are the images, so make sure that they are strong ones that are eye_catching. Color newsletters also tend to be more appealing than those in black and white, though they can cost a bit more to print.
This approach tends to work better for articles that are jam packed with information and/or those that take a broad, aerial view of the topic, but it can also work with articles that are a close up view of one specific topic. For example, I've written many articles on how to create an effective resource box, and from that one very laser beamed topic I have branched off articles on extremely specific elements of that already specific topic. I assure you, no matter what your article is about, you can write about it more in depth in a new article.