The next thing which comes in the notice of the visitors is the header of the layout. For this very reason you have to choose a business template that has option to highlight your offers on products or services in short in that place. You may take a portion to place a short video to give a glimpse of things. Placing animation in place of static images always work.
The Details are important _ Pay special attention to the details. They affect your readers very much. Details like alignment of the texts and the number of lines which your paragraphs include, can make readers bored or can interest them. Try not to make your paragraphs longer than 3 or 4 lines. When your paragraphs are short, people will read them easily. But if they are long, it will seem overwhelming to people. The colors you use in your newsletter design is important as well. So you should know a little about colors psychology. It's not hard. You must already know about the effect of every color on people, before designing or choosing your newsletter template.